Mechanobiology and the influence of the physical environment on individual cells and multicellular systems, attract researchers from various scientific fields, including biology, physics and engineering. Their common aim is to understand how mechanical forces are integrated in biological signalling and to describe complex cellular behaviours with physical models. The complexity of wiring between cells and the extracellular environment is being unravelled along with the development of new engineering technologies enabling the nanoscale control and measurements of physical parameters.
This workshop will discuss recent advances and current challenges in nanoengineering applied to biological systems and mechanobiology: from the development of new methods to their application for the discovery of molecular mechanisms.
08.45 – 09.00
A. Ferrari - M. Vassalli
Introduction
09.00 – 9.45
M.T. Raimondi
Nanoscale manipulation of stem cell shape
9.45 – 10.30
P. Glynne-Jones
Acoustic radiation forces for mechanobiology
10.30 – 11.15
H. Eghlidi
Controlling and dictating the motion of nanoscale viruses in a liquid with single virus resolution
11.15 – 11.30
Coffee break
11.30 – 12.15
P. Roca-Cusachs
Understanding the cell-extracellular matrix mechanical link: from molecular roles to emerging behaviors
12.15 – 12.45
D. Carugo
Micro-engineered devices for ultrasound-mediated drug delivery: production, characterisation and bio-physical effects
12.45 – 13.15
M. Paturzo
Label-free cell behavior analysis by digital holographic methods
15.00 – 15.45
G.Scita
Endocytic control of collective motility
15.45 – 16.30
A.Nicolas
Multiscaled confinement and guidance of cells by gradients of rigidity
16.30 – 17.15
C. Canale
Single cell force spectroscopy suggests the unpredicted affection of cells adhesion capability induced by toxic amyloid oligomers
17.15 – 17.30
Coffee break
17.30 – 18.00
Nanosurf AG
AFM beyond imaging
18.00 – 18.30
T. Lendenmann
Confocal reference-free Traction Force Microscopy
18.30 – 19.00
A. Taubenberger
Studying mechanical aspects of adipogenesis
09.00 – 09.45
J.Guck
Feeling for cell function: mechanical phenotyping at 1000 cells/sec
09.45 – 10.30
D.Arosio
Chloride and pH imaging from live neurons to brain
10.30 – 10.45
Coffee break
10.45 – 11.15
M. Panagiotakopoulou
Paramorphotic youth: a new mechanism of tumor migration unveiled in a nanoprinted model
11.15 – 11.45
G.Palazzolo
Shaping the extracellular microenvironment to control cell function
11.45 – 12.15
R. Oria
Force loading explains how substrate rigidity and ligand nano-distribution regulate cell response
12.15 – 12.30
Concluding Remarks
Hotel Cenobio dei Dogi - Camogli - Italy
Via N. Cuneo, 34 Camogli, (GE) 16032
Arrival: April 3, Sunday afternoon
Departure: April 5, after lunch