Nanoengineering for Mechanobiology
Camogli, April 3-5, 2016

Aim of the meeting


Mechanobiology and the influence of the physical environment on individual cells and multicellular systems, attract researchers from various scientific fields, including biology, physics and engineering. Their common aim is to understand how mechanical forces are integrated in biological signalling and to describe complex cellular behaviours with physical models. The complexity of wiring between cells and the extracellular environment is being unravelled along with the development of new engineering technologies enabling the nanoscale control and measurements of physical parameters.

This workshop will discuss recent advances and current challenges in nanoengineering applied to biological systems and mechanobiology: from the development of new methods to their application for the discovery of molecular mechanisms.

Invited Speakers


Program


Monday 4, 8:45-13:00
Nanoscale manipulation of biological objects

08.45 – 09.00 A. Ferrari - M. Vassalli
Introduction

09.00 – 9.45 M.T. Raimondi
Nanoscale manipulation of stem cell shape

9.45 – 10.30 P. Glynne-Jones
Acoustic radiation forces for mechanobiology

10.30 – 11.15 H. Eghlidi
Controlling and dictating the motion of nanoscale viruses in a liquid with single virus resolution

11.15 – 11.30
Coffee break

11.30 – 12.15 P. Roca-Cusachs
Understanding the cell-extracellular matrix mechanical link: from molecular roles to emerging behaviors

12.15 – 12.45 D. Carugo
Micro-engineered devices for ultrasound-mediated drug delivery: production, characterisation and bio-physical effects

12.45 – 13.15 M. Paturzo
Label-free cell behavior analysis by digital holographic methods

Monday 4, 15:00-18:45
Mechanical sensing and transduction

15.00 – 15.45 G.Scita
Endocytic control of collective motility

15.45 – 16.30 A.Nicolas
Multiscaled confinement and guidance of cells by gradients of rigidity

16.30 – 17.15 C. Canale
Single cell force spectroscopy suggests the unpredicted affection of cells adhesion capability induced by toxic amyloid oligomers

17.15 – 17.30
Coffee break

17.30 – 18.00 Nanosurf AG
AFM beyond imaging

18.00 – 18.30 T. Lendenmann
Confocal reference-free Traction Force Microscopy

18.30 – 19.00 A. Taubenberger
Studying mechanical aspects of adipogenesis

Tuesday 5, 9:00-12:30
Biophysical control of cellular function

09.00 – 09.45 J.Guck
Feeling for cell function: mechanical phenotyping at 1000 cells/sec

09.45 – 10.30 D.Arosio
Chloride and pH imaging from live neurons to brain

10.30 – 10.45
Coffee break

10.45 – 11.15 M. Panagiotakopoulou
Paramorphotic youth: a new mechanism of tumor migration unveiled in a nanoprinted model

11.15 – 11.45 G.Palazzolo
Shaping the extracellular microenvironment to control cell function

11.45 – 12.15 R. Oria
Force loading explains how substrate rigidity and ligand nano-distribution regulate cell response

12.15 – 12.30
Concluding Remarks

Venue


Hotel Cenobio dei Dogi - Camogli - Italy

Via N. Cuneo, 34 Camogli, (GE) 16032

Arrival: April 3, Sunday afternoon
Departure: April 5, after lunch

Camogli